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Symbol
Name
ID
Pdcd10
programmed cell death 10
MGI:1928396
Phenotype annotations related to cardiovascular system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Cerebral hemorrhage
Cerebral cavernous malformation
Disease(s) Associated with PDCD10
cerebral cavernous malformation 3

Mouse Phenotypes
cardiovascular system phenotype
abnormal dorsal aorta morphology
dilated dorsal aorta
abnormal brain vasculature morphology
abnormal retina vasculature morphology
abnormal intersomitic vessel morphology
abnormal pericyte morphology
abnormal angiogenesis
abnormal developmental vascular remodeling
abnormal vascular branching morphogenesis
abnormal cardinal vein morphology
abnormal vascular endothelial cell migration
abnormal vasculogenesis
abnormal vitelline vasculature morphology
dilated vasculature
abnormal myocardium layer morphology
myocardial trabeculae hypoplasia
thin myocardium
abnormal cardiac jelly morphology
abnormal endocardium morphology
enlarged pericardium
Availability Mouse Genotype
Pdcd10tm1.1Wami/Pdcd10tm1.1Wami
Pdcd10tm1Arte/Pdcd10tm1Arte
Tg(Cdh5-cre/ERT2)1Rha/0  (conditional)
Pdcd10tm1Kwhi/Pdcd10tm1Kwhi
Tg(Tek-cre)1Ywa/?  (conditional)
*
Pdcd10tm1Kwhi/Pdcd10tm1Kwhi
Nfatc1tm1.1(cre)Bz/Nfatc1+  (conditional)
Pdcd10tm1Wami/Pdcd10tm1Wami
Tg(Tek-cre)12Flv/0  (conditional)
Pdcd10tm1Wami/Pdcd10tm1Wami
Taglntm2(cre)Yec/Tagln+  (conditional)
*
Pdcd10tm1Wami/Pdcd10tm1Wami
Tg(GFAP-cre)25Mes/0  (conditional)
Pdcd10tm1Wami/Pdcd10tm1Wami
Emx1tm1(cre)Krj/Emx1+  (conditional)
Pdcd10tm1Kwhi/Pdcd10tm1.1Kwhi
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory